2023
Halonen P, Jämsen E, Enroth L, Jylhä M. 2023. Agreement between self-reported information and health register data on chronic diseases in the oldest old. Clinical Epidemiology 785-794. https://doi.org/10.2147/CLEP.S410971
Enroth L, Halonen P, Tiainen K, Raitanen J, Jylhä M. 2023. Cohort profile: The Vitality 90+ Study. A cohort study on health and living conditions of the oldest old in Tampere, Finland. BMJ open, 13(2). http://dx.doi.org/10.1136/bmjopen-2022-068509
Hatavara M. 2023. How to Narrate a Healthy Life: Life Stories and Mental Health in Interviews with the Elderly Aged 90+. In Narrative and Mental Health: Reimagining Theory and Practice, 153-173. Oxford University Press.
Vargese S, Jylhä M, Raitanen J, Enroth L, Halonen P, Aaltonen M. 2023. Dementia-related disability in the population aged 90 years and over: Differences over time and the role of comorbidity in the Vitality 90+ Study. BMC Geriatrics 23(1), 276. https://doi.org/10.1186/s12877-023-03980-5
2022
Halonen P, Enroth L, Jämsen E, Vargese S, Jylhä M. 2022. Dementia and related comorbidities in the population aged 90 and over in the Vitality 90+ Study, Finland: patterns and trends from 2001 to 2018. Journal of Aging and Health. https://doi.org/10.1177/08982643221123451
2021
Enroth L, Fors S 2021. Trends in the social class inequalities in disability and self-rated health: Repeated cross-sectional surveys from Finland and Sweden 2001-2018. International Journal of Public Health, 66:645513. https://doi.org/10.3389/ijph.2021.645513
Enroth L, Pulkki J 2021. Aistivaikeudet, arki ja toimintakyky 90 vuotta täyttäneillä. Gerontologia, 35(2), 121–137. https://doi.org/10.23989/gerontologia.96102 (Sensory difficulties, everyday life and functional ability among people aged 90+)
Enroth L, Raitanen J, Halonen P, Tiainen K, Jylhä M 2021. Trends of Physical Functioning, Morbidity, and Disability-Free Life Expectancy Among the Oldest Old: Six Repeated Cross-Sectional Surveys Between 2001 and 2018 in the Vitality 90+ Study. J Gerontol A Biol Sci Med Sci, 76(7), 1227-1233. https://doi.org/10.1093/gerona/glaa144
Hyvärinen M, Hatavara M, Rautajoki H 2021. Positioning with Master and Counter-Narratives. Narrative Inquiry, 31(1), 97–125. https://doi.org/10.1075/ni.20014.hyv
Nevalainen T, Autio A, Puhka M, Jylhä M, Hurme M 2021. Composition of the whole transcriptome in the human plasma: Cellular source and modification by aging. Exp Gerontol 143:111119. https://doi.org/10.1016/j.exger.2020.111119
Rautajoki H, Hyvärinen M 2021. Aspects of voice in the use of positioning in polyphonic storytelling. Ventriloquial moves within a biographical interview. Journal of Interdisciplinary Voice Studies, 6(1), 55-73. https://doi.org/10.1386/jivs_00037_1
2020
Autio A, Nevalainen T, Mishra BH, Jylhä M, Flinck H, Hurme M 2020. Effect of aging on the transcriptomic changes associated with the expression of the HERV-K (HML-2) provirus at 1q22. Immunity & ageing, 17(1). https://doi.org/10.1186/s12979-020-00182-0
Lisko I, Törmäkangas T, Jylhä M 2020. Structure of self-rated health among the oldest old: Analyses in the total population and those living with dementia. SSM – Population Health 11:100567. https://doi.org/10.1016/j.ssmph.2020.100567
Raitanen J, Stenholm S, Tiainen K, Jylhä M, Nevalainen J 2020. Longitudinal change in physical functioning and dropout due to death among the oldest old: a comparison of three methods of analysis. European Journal of Ageing, (17), 207–216. https://doi.org/10.1007/s10433-019-00533-x
2019
Enroth L, Veenstra M, Aartsen M, Kjær AA, Juul Nilsson C, Fors S 2019. Are there educational disparities in health among the oldest old? Evidence from the Nordic countries. European Journal of Ageing, (16), 415–424. https://doi.org/10.1007/s10433-019-00517-x
Halonen P, Raitanen J, Enroth L, Jämsen E, Jylhä M 2019. Chronic conditions and multimorbidity in population aged 90 years and over: associations with mortality and long-term care admission. Age and Ageing, 48(4), 564–570. https://doi.org/10.1093/ageing/afz019
Hoogendijk EO, van der Noordt M, Onwuteaka-Philipsen Bregje D, Deeg Dorly JH, Huisman M, Enroth L, Jylhä M 2019. Sex differences in healthy life expectancy among nonagenarians: A multistate survival model using data from Vitality 90+ study. Experimental Gerontology, 116, 80–85. https://doi.org/10.1016/j.exger.2018.12.015
Hyvärinen M, Hatavara M, Rautajoki, H 2019. Kerronta, asemointi ja haastattelun analyysi [Narration, Positioning and the Analysis of Interviews]. Sosiologia 56, no. 1: 6–25. http://urn.fi/URN:NBN:fi:tuni-201904251540
Jylhä M, Enroth L, Halonen P 2019. Vanhoista vanhimpien terveys ja toimintakyky. Duodecim, 135 (11), 1085–1091. http://urn.fi/URN:NBN:fi:tuni-201911125883
Nevalainen T, Autio A, Kummola L, Salomaa T, Junttila I, Jylhä M, Hurme M 2019. CD27- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males. Immun Ageing 16:19-019-0159-6. eCollection 2019. https://doi.org/10.1186/s12979-019-0159-6
Ozsait-Selcuk B, Komurcu-Bayrak E, Jylhä M, Luukkaala T, Perola M, Kristiansson K, Mononen N, Hurme M, Kähönen M, Goebeler S et al 2019. The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study. Annals of human genetics, 83(1), 34–45. https://doi.org/10.1111/ahg.12282
Tuominen, K, Pirhonen, J 2019. Who would take a 90-year-old? Community-dwelling nonagenarians’ perceptions of social relationships. International Journal of Ageing and Later Life, 13(11), 111–137. http://doi.org/10.3384/ijal.1652-8670.18387
2018
Enroth L, Aaltonen M, Raitanen J, Nosraty L, Jylhä M 2018. Does use of long-term care differ between occupational classes among the oldest old? Vitality 90+ Study. European Journal of Ageing, 15, 143–153. https://doi.org/10.1007/s10433-017-0445-0
Nevalainen T, Autio A, Mishra BH, Marttila S, Jylhä M, Hurme M 2018. Aging-associated patterns in the expression of human endogenous retroviruses. PLoS One 13:e0207407. https://doi.org/10.1371/journal.pone.0207407
2017
Halonen, P, Enroth, L, Jylhä, M, Tiainen K 2017. Pitkäaikaissairaudet ja monisairastavuus hyvin vanhoilla sekä niiden yhteys toimintakykyyn ja itse arvioituun terveyteen-Tervaskannot 90+ -tutkimus. Gerontologia, 31 (4), 269–281. https://doi.org/10.23989/gerontologia.65943
Kauppi M, Raitanen J, Stenholm S, Aaltonen M, Enroth L, Jylhä M 2017. Predictors of long-term care among nonagenarians: the Vitality 90 + Study with linked data of the care registers. Aging clinical and experimental research, 30(8), 913–919. https://doi.org/10.1007/s40520-017-0869-6
Lisko, I, Tiainen, K, Raitanen, J, Jylhävä, J, Hurme, M, Hervonen, A, Stenholm, S 2017. Body Mass Index and Waist Circumference as Predictors of Disability in Nonagenarians: The Vitality 90+ Study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 72(11), 1569–1574. https://doi.org/10.1093/gerona/glx032
Marttila S, Nevalainen T, Jylhävä J, Kananen L, Jylhä M, Hervonen A, Hurme M 2017. Human endogenous retrovirus HERV-K(HML-2) env expression is not associated with markers of immunosenescence. Experimental Gerontology, 97, 60–63. https://doi.org/10.1016/j.exger.2017.07.019
Nevalainen T, Kananen L, Marttila S, Jylhava J, Mononen N, Kahonen M, Raitakari OT, Hervonen A, Jylha M, Lehtimaki T et al 2017. Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals. Clinical Epigenetics, 9(1), 20. https://doi.org/10.1186/s13148-016-0301-7
Nosraty L, Pulkki J, Raitanen J, Enroth L, Jylhä M 2017. Successful Aging as a Predictor of Long-Term Care Among Oldest Old: The Vitality 90+ Study. Journal of applied gerontology, 38(4), 553–571. https://doi.org/10.1177/0733464817716968
2016
Enroth L, Raitanen J, Hervonen A, Lehtimäki T, Jylhävä J, Hurme M, Jylhä M 2016. Cardiometabolic and Inflammatory Biomarkers as Mediators Between Educational Attainment and Functioning at the Age of 90 Years. J Gerontol A Biol Sci Med Sci 71, 412–419. https://doi.org/10.1093/gerona/glv105
Jylhävä J, Kananen L, Raitanen J, Marttila S, Nevalainen T, Hervonen A, Jylhä M, Hurme M 2016. Methylomic predictors demonstrate the role of NF-κB in old-age mortality and are unrelated to the aging-associated epigenetic drift. Oncotarget, 7(15), 19228–41. https://doi.org/10.18632/oncotarget.8278
Kananen L, Marttila S, Nevalainen T, Kummola L, Junttila I, Mononen N, Kähönen M, Raitakari OT, Hervonen A, Jylhä M et al 2016. The trajectory of the blood DNA methylome ageing rate is largely set before adulthood: evidence from two longitudinal studies. Age, 38(3), 65. https://doi.org/10.1007/s11357-016-9927-9
Nevalainen T, Kananen L, Marttila S, Jylhävä J, Jylhä M, Hervonen A, Hurme M 2016. Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals. PLoS ONE, 11, e0167028. https://doi.org/10.1371/journal.pone.0167028
2015
Enroth L, Raitanen J, Hervonen A, Nosraty L, Jylhä M 2015. Is Socioeconomic Status a Predictor of Mortality in Nonagenarians? The Vitality 90+ Study. Age and Ageing, 44(1), 123–129. https://doi.org/10.1093/ageing/afu092
Kananen L, Nevalainen T, Jylhävä J, Marttila S, Hervonen A, Jylhä M, Hurme M 2015. Cytomegalovirus infection accelerates epigenetic aging. Exp Gerontol 72:227-229. Experimental Gerontology, 72(S: C), 227–29. https://doi.org/10.1016/j.exger.2015.10.008
Lisko I, Stenholm S, Raitanen J, Hurme M, Hervonen A, Jylhä M, Tiainen K 2015. Association of Body Mass Index and Waist Circumference With Physical Functioning: The Vitality 90+ Study. Journal of Gerontology A Biological Sciences and Medical Sciences, 70(7), 885–891. https://doi.org/10.1093/gerona/glu202
Marttila S, Kananen L, Häyrynen S, Jylhävä J, Nevalainen T, Hervonen A, Jylhä M, Nykter M, Hurme M 2015. Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression. BMC Genomics, 16(1), [179]. https://doi.org/10.1186/s12864-015-1381-z
Marttila S, Kananen L, Jylhävä J, Nevalainen T, Hervonen A, Jylhä M, Hurme M 2015. Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny. Oncotarget, 6(31), 30557–30567. https://doi.org/10.18632/oncotarget.5905
Marttila S, Nevalainen T, Kananen L, Jylhävä J, Jylhä M, Hervonen A, Ilonen J, Hurme M 2015. Number of sons contributes to ageing-associated inflammation. Scientific Reports, 5(8631). https://doi.org/10.1038/srep08631
Nevalainen T, Kananen L, Marttila S, Jylhä M, Hervonen A, Hurme M, Jylhävä J 2015. Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study. AGE, 37(4), 9814. [76]. https://doi.org/10.1007/s11357-015-9814-9
Nosraty L, Enroth L, Raitanen J, Hervonen A, Jylhä M 2015. Do Succesful Agers Live Longer? The Vitality 90+ Study. Journal of Aging and Health, 27(1), 35–53. https://doi.org/10.1177/0898264314535804
Nosraty L, Raittila T, Jylhä M, Lumme-Sandt K 2015. Perceptions by the oldest-old of successful aging. Journal of Aging Studies, 32, 50–58. https://doi.org/10.1016/j.jaging.2015.01.002
Tiainen K, Raitanen J, Vaara E, Hervonen A, Jylhä M 2015. Longitudinal changes in mobility among nonagenarians: the Vitality 90+ Study. BMC Geriatrics, 15, 1–8. https://doi.org/10.1186/s12877-015-0116-y
2014
Jylhävä J, Raitanen J, Marttila S, Hervonen A, Jylhä M, Hurme M 2014. Identification of a prognostic signature for old-age mortality by integrating genome-wide transcriptomic data with the conventional predictors: the Vitality 90+ Study. Bmc Medical Genomics, 11(54), 54. https://doi.org/10.1186/1755-8794-7-54
Marttila S, Jylhävä J, Kananen L, Hervonen A, Jylhä M, Hurme M 2014. Molecular mechanisms associated with the strength of the anti-CMV response in nonagenarians. Immunity & Ageing, 11(1), 1–6. https://doi.org/10.1186/1742-4933-11-2
2013
Enroth L, Raitanen J, Hervonen A, Jylhä M 2013. Do socioeconomic health differences persist in nonagenarians. The Journals of Gerontology Series B : Psychological Sciences and Social Sciences, 68(5), 837–847. https://doi.org/10.1093/geronb/gbt067
Galenkamp H, Deeg DJH, Huisman M, Hervonen A, Braam AW, Jylhä M 2013. Is self-rated health still sensitive for changes in disease and functioning among nonagenarians? The Journals of Gerontology Series B : Psychological Sciences and Social Sciences, 68(5), 848–858. https://doi.org/10.1093/geronb/gbt066.
Jylha M, Enroth L and Luukkaala T 2013. Trends of functioning and health in nonagenarians- the Vitality 90+ Study. In J-M. Robine, C. Jagger, & E. Crimmins (Eds.), Annual Review of Gerontology and Geriatrics, 313–332. Springer Publishing Company. https://doi.org/10.1891/0198-8794.33.313
Jylhävä J, Nevalainen T, Marttila S, Jylhä M, Hervonen A, Hurme M 2013. Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty. Aging Cell, 12(3), 388–397. https://doi.org/10.1111/acel.12058
Kämppä N, Mäkelä KM, Lyytikäinen LP, Peltonen N, Hautamäki J, Seppälä I, Mononen N, Goebeler S, Karhunen PJ, Hervonen A et al 2013. Vascular cell adhesion molecule 1, soluble Fas and hepatocyte growth factor as predictors of mortality in nonagenarians: the Vitality 90+ study. Experimental Gerontology, 48(11), 1167–72. https://doi.org/10.1016/j.exger.2013.07.009
Lisko I, Tiainen K, Stenholm S, Luukkaala T, Hurme M, Lehtimäki T, Hervonen A, Jylhä M 2013. Are body mass index, waist circumference and waist-to-hip ratio associated with leptin in 90-year-old people? European Journal of Clinical Nutrition, 67(4), 420–422. https://doi.org/10.1038/ejcn.2013.39
Tiainen K, Luukkaala T, Hervonen A, Jylhä M 2013. Predictors of mortality in men and women aged 90 years and older: nine-year follow-up. Age and ageing, 42(4), 468–475. https://doi.org/10.1093/ageing/aft030
2012
Helminen S, Sarkeala T, Enroth L, Hervonen A, Jylhä M 2012. Vanhoista vanhimpien terveys ja elämätilanne. Tuloksia vuoden 201 Tervaskannot 90+- tutkimuksesta. Gerontologia 26(3):162–171. http://urn.fi/URN:NBN:fi:uta-201702131130
Jylhävä J, Jylhä M, Lehtimäki T, Hervonen A, Hurme M 2012. Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians. Experimental Gerontology, 47(5), 372–378. https://doi.org/10.1016/j.exger.2012.02.011
Lisko I, Tiainen K, Stenholm S, Luukkaala T, Hurme M, Lehtimäki T, Hervonen A, Jylhä M 2012. Inflammation, adiposity and mortality in the oldest old. Rejuvenation Research, 15(5), 445–452. https://doi.org/10.1089/rej.2011.1310
Nosraty L, Hervonen A, Jylhä M 2012. Is there successful aging for nonagenarians? Vitality 90+ study. Journal of Aging Research, [ID 868797]. https://doi.org/10.1155/2012/868797
Vuorisalmi M, Sarkeala T, Hervonen A, Jylhä M 2012. Among nonagenarians, congruence between self-rated health and proxy-rated health was low but both predicted mortality. Journal of Clinical Epidemiology, 65(5), 553–559. https://doi.org/10.1016/j.jclinepi.2011.11.001
-2011
Jylhävä J, Kotipelto T, Raitala A, Jylhä M, Hervonen A, Hurme M 2011. Aging is associated with quantitative and qualitative changes in circulating cell-free DNA: the Vitality 90+ study. Mech Ageing, 132(1-2), 20–26. https://doi.org/10.1016/j.mad.2010.11.001
Marttila S, Jylhävä J, Pesu M, Hämäläinen S, Jylhä M, Hervonen A, Hurme M 2011. IL-7 concentration is increased in nonagenarians but is not associated with markers of T cell immunosenescence. Experimental gerontology, 46(12), 1000–1002. https://doi.org/10.1016/j.exger.2011.09.004
Sarkeala T, Nummi T, Vuorisalmi M, Hervonen A, Jylhä M 2011. Disability trends among nonagenarians in 2001-2007: Vitality 90 study. European Journal of Ageing, 8(2), 87–94. https://doi.org/10.1007/s10433-011-0188-2
Tiainen K, Hurme M, Hervonen A, Luukkaala T, Jylhä M 2010. Inflammatory markers and physical performance among nonagenarians. J Gerontol A Biol Sci Med Sci 65: 658-663. https://doi.org/10.1093/gerona/glq056.
Jylhävä J, Eklund C, Jylhä M, Hervonen A, Hurme M 2010. Expression profiling of immune-associated genes in peripheral blood mononuclear cells reveals baseline differences in co-stimulatory signalling between nonagenarians and younger controls: the vitality 90+ study. Biogerontology, 11(6), 671–677. https://doi.org/10.1007/s10522-010-9274-7
Jylhävä J, Eklund C, Jylhä M, Hervonen A, Lehtimäki T, Karhunen P, Hurme M 2009. Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ study. Experimental Gerontology, 44(4), 297–9. https://doi.org/10.1016/j.exger.2008.10.006
Jylhä M, Paavilainen P, Lehtimäki T, Goebeler S, Karhunen PJ, Hervonen A, Hurme M 2007. Interleukin-1 receptor antagonist, interleukin-6, and C-reactive protein as predictors of mortality in nonagenarians: the vitality 90+ study. J Gerontol A Biol Sci Med Sci., 62A(9), 1016–1021. https://doi.org/10.1093/gerona/62.9.1016
Niemi AK, Hervonen A, Hurme M, Karhunen PJ, Jylhä M, Majamaa K 2003. Mitochondrial DNA polymorphisms associated with longevity in a Finnish population. Human Genetics, 112(1), 29–33. https://doi.org/10.1007/s00439-002-0843-y