International Journal Publications
International Conference Publications
International Conference Abstracts and Poster Presentations
N. Broguiere, G. Palazzolo, and M. Zenobi-Wong, “Engineered hydrogels supporting fast neurite extension,” Neuroscience 2015, Chicago, IL, Oct. 17-21, 2015, program/poster 46.08/D35. Download the abstracts of the presentation day.
N. Broguiere, G. Palazzolo, and M. Zenobi-Wong, “3D neural networks in engineered extracellular matrices,” in Bernstein Conference 2015 Abstract Book, Heidelberg, Germany, Sept. 15-17, 2015, pp. 183-184. Download the Abstract Book.
A. Chilian, A. Katai, and P. Husar, “Investigation of cultured neuronal networks and their dynamics induced by novel stimulation paradigms,” in Bernstein Conference 2015 Abstract Book, Heidelberg, Germany, Sept. 15-17, 2015, pp. 223. Download the Abstract Book.
L. Demkó, D. Ling, S. Weydert, C. Forró, and J. Vörös, “Signal propagation in small reproducible neuronal networks,” in Bernstein Conference 2015 Abstract Book, Heidelberg, Germany, Sept. 15-17, 2015, pp. 78-79. Download the Abstract Book.
T. Just and P. Husar, “Signal acquisition and measurement system for neural networks in vitro,” in Bernstein Conference 2015 Abstract Book, Heidelberg, Germany, Sept. 15-17, 2015, pp. 224. Download the Abstract Book.
F. E. Kapucu, J. E. Mikkonen, J. M. A. Tanskanen, and J. A. K. Hyttinen, “Entropy based quantification of in vivo and in vitro neuronal bursts,” Bernstein Conference 2015 Abstract Book, Heidelberg, Germany, Sept. 15-17, 2015 pp. 142-143. Download the Abstract Book.
E. Räisänen, J. A K Hyttinen, and Kerstin Lenk, “Modeling a single tripartite synapse,” Bernstein Conference 2015 Abstract Book, Heidelberg, Germany, Sept. 15-17, 2015, pp. 70. Download the Abstract Book.
J. M. A. Tanskanen, F. E. Kapucu, and J. A. K. Hyttinen, “An algorithm to automatically set neuronal action potential spike detection thresholds,” Bernstein Conference 2015 Abstract Book, Heidelberg, Germany, Sept. 15-17, 2015, pp. 143-144. Download the Abstract Book.
I. Vornanen, K. Lenk, and J. A. K. Hyttinen, “Simulations on different electrode arrangements of microelectrode arrays,” in Bernstein Conference 2015 Abstract Book, Heidelberg, Germany, Sept. 15-17, 2015, pp. 63-64. Download the Abstract Book.
N. Broguiere, G. Palazzolo, and M. Zenobi, “Optimization of hydrogels for fast 3D neurite extension of encapsulated neurons,” 4th TERMIS World Congress, Boston, MA, Sept. 8-11, 2015.
E. A. Räisänen, J. A. K. Hyttinen, and K. Lenk, “Modeling presynapse–astrocyte interactions,” in Neuroinformatics 2015 Abstract Book, Cairns, Australia, Aug. 22, 2015, pp. 122-123. Download the Abstract Book.
I. Vornanen, K. Lenk, and J. A. K. Hyttinen, “Simulating electrode arrangements on microelectrode arrays,” 24th Annual Computational Neuroscience Meeting, Prague, Czech Republic, July 18-23, 2015.
T. Paavilainen, D. Fayuk, A. Pelkonen, M. Mäkinen, L. Ylä-Outinen, and Susanna Narkilahti, “Effect of human pluripotent stem cell -derived astrocytes in the development and functionality of neuronal networks,” XII European Meeting on Glial Cells in Health and DiseaseBilbao, Spain, July 15-18, 2015, abstract T08-29A. Abstract search.
A. Pelkonen, T. Paavilainen, D. Fayuk, M. Mäkinen, L. Ylä-Outinen, and Susanna Narkilahti, “Role of astrocytes in functional maturation of human neural network,” XII European Meeting on Glial Cells in Health and Disease, Bilbao, Spain, July 15-18, 2015, abstract T08-31A. Abstract search.
E. Räisänen, K. Lenk, and J. Hyttinen, “Modeling neuron-astrocyte interactions at network level,” XII European Meeting on Glial Cells in Health and Disease, Bilbao, Spain, July 15-18, 2015, abstract T08-32A. Abstract search.
S. Narkilahti, A. Pelkonen, T. Paavilainen, D. Fayuk, and M. Mäkinen, “Role of astrocytes in formation of functional neuronal networks in vitro,” in ISSCR Poster Abstract Book, Stockholm, Sweden, June 24-27, 2015, pp. 464. Download the abstract book.
L. Demkó, H. Dermutz, C. Forró, S. Weydert, and J. Vörös, “Towards engineered neuronal networks – from realization to modeling,” Post-Doc-Day 2015, Au, Switzerland, May 21, 2015.
H. Bartsch, M. Baca, D. Stöpel, A. Schober, and J. Müller, “LTCC based multi-electrode arrays for in-vitro cell culture,” 11th International Conference and Exhibition on Ceramic Interconnect and Ceramic Microsystems Technologies, Dresden, Germany, Apr. 20-23, 2015.
K. Lenk, I. Vornanen, E. Räisänen, and J. A. K. Hyttinen, “INEX – A computational model to simulate spatial neuronal-astrocytic activity,” in Proceedings of the 11th Göttingen Meeting of the German Neuroscience Society, Göttingen, Germany, Mar. 18-21, 2015, abstract S28_2-4. Download the Proceedings.
H. Dermutz, R. Grüter, L. Demko, C. Forro, M. Aebersold, S. Weydert, E. Lilli, A. M. Truong, T. Zambelli, and J. Vörös, “Approaches towards engineered neuron networks in vitro,” Swiss Society for Neuroscience Annual Meeting 2015, Fribourg, Switzerland, Jan 24, 2015, pp. 4. Download the abstracts.
M. J. Aebersold, H. Dermutz, J. F. Saenz Cogollo, L. Demkó, Z. Tomaso, and J. Vörös, “Engineered neuronal networks – Connecting, stimulating, and recording neurons,” Swiss Society for Neuroscience Annual Meeting 2015, Fribourg, Switzerland, Jan 24, 2015, pp. 21-22. Download the abstracts.
H. Dermutz, R. Grüter, E. Lilli, A. Truong, L. Demkó, T. Zambelli, and J. Vörös, “In vitro guidance of developing neural networks,” in AFM BioMed 2014 Conference Program, San Diego, CA, Dec. 13-17, 2014, pp. 40. Download the Conference Program.
K. Lenk, I. Vornanen, E. Räisänen, and J. A. K. Hyttinen “INEX – A simple but effective stochastic model to simulate neuronal-astrocytic activity,” HBP Workshop on Stochastic Neural Computation, Paris, France, Nov. 27-28, 2014.
L. Demkó, H. Dermutz, C. Forró, S. Weydert, T. Zambelli, and J. Vörös, “Signal propagation in small neuron networks with memory function – characterization and modeling,” Neuroscience 2014, Washington, DC, Nov. 15-19, 2014.
C. Forró, L. Demkó, H. Dermutz, and J. Vörös, “A simple technique for directed axonal guidance on multi-electrode arrays with arbitrary topology,” Neuroscience 2014, Washington, DC, Nov. 15-19, 2014.
S. Weydert, C. Forró, J. Chaaban, H. Dermutz, L. Demkó, and J. Vörös, “Electrically driven axonal outgrowth on multi-electrode arrays,” Neuroscience 2014, Washington, DC, Nov. 15-19, 2014.
K. Lenk, I. Vornanen, E. Räisänen, and J. Hyttinen, “INEX – A simple but effective computational model to simulate neuronal-astrocytic activity,” Virtual Physiological Human Conference 2014, Trondheim, Norway, Sept. 9-12, 2014.
K. Lenk, L. Ylä-Outinen, L. H. B. Tietz, S. Narkilahti, and J. A. K. Hyttinen, “Simulation of matured neuronal cell networks derived from human pluripotent stem cells,” in Bernstein Conference 2014 Program and Abstracts, Göttingen, Germany, Sept. 3-5, 2014, pp. 181. Download the Program and Abstracts Book.
H. Dermutz, R. Grüter, A. Truong, L. Demkó, T. Zambelli, and J. Vörös, “Dynamic pattern design – A new tool for in situ guidance of neurites,” NPlast summer school on “Synapse dynamics in circuit formation, learning and disease“, Lago Di Como, Italy, July 9-12, 2014.
M. Baca, H. Bartsch, T. Porzig, A. Williamson, and A. Schober, “3D Multi electrode arrays,” in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays , Reutlingen, Germany, July 1-4, 2014, pp. 310-311. Download the Proceedings.
L. Demkó, C. Forró, H. Dermutz, and J. Vörös, “Directed neuronal networks on multi-electrode arrays,” in Proc. 9th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, July 1-4, 2014, pp. 341. Download the Proceedings.
T. Just and P. Husar, “Amplifier ASIC for real 3D-multichannel-MEA,” in Proc. 9th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, July 1-4, 2014, pp. 320-321. Download the Proceedings.
T. Joki, P. Salonen, T. Toimela, R. Äänismaa, T. Ylikomi, and S. Narkilahti, “Human pluripotent stem cell derived neural cells obtained either using adherent or neurosphere based differentiation have ability to form Spontaneously active neuronal networks,” in Proc. 9th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, July 1-4, 2014, pp. 342-343. Download the Proceedings.
K. Lenk, L. Ylä-Outinen, L. H. B. Tietz, S. Narkilahti, and , J. A. K. Hyttinen, “Simulation of hPSC derived neuronal networks with short and long reaching axons,” in Proc. 9th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, July 1-4, 2014, pp. 219-218. Download the Proceedings.
I. Vornanen, J. M. A. Tanskanen, J. Hyttinen, and K. Lenk, “Comparison of neuronal dynamics in 2D and 3D in silico networks,” in Proc. 9th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, July 1-4, 2014, pp. 204-205. Download the Proceedings.
L. Demkó, C. Forró, H. Dermutz, and J. Vörös, “Building of hybrid networks with controlled topology“, Swiss Working Group for Surface and Interface Science Annual Meeting 2014, Fribourg, Switzerland, Jan. 25, 2014.
M. J. Aebersold, H. Dermutz, J. F. Saenz Cogollo, L. Demkó, T. Zambelli, J. Vörös, “Localized chemical stimulation and mapping of neuronal cultures combining FluidFM with MEA,” Neuroscience 2013, San Diego, CA, Nov. 9-13, 2013.
H. Dermutz, R. Grüter, A. Troung, L. Demko, T. Zambelli, and J. Vörös, “Pattern and guide – Getting control over a developing neuron network,” Neuroscience 2013, Nov 9-13, 2013, San Diego, CA.
D. A. Fayuk, M. Mäkinen, C. Prajapati, S. Penkki, A. Hyysalo, L. Ylä-Outinen, and S. Narkilahti, “Characterization of functional human neuronal networks In vitro,” Neuroscience 2013, Nov 9-13, 2013, San Diego, CA
M. E.-L. Mäkinen, L. Ylä-outinen, D. Fayuk, and S. Narkilahti, “Development of network connectivity in human pluripotent stem cell derived neural networks,” Neuroscience 2013, Nov 9-13, 2013, San Diego, CA
K. Lenk, B. Priwitzer, S. Narkilahti, O. H.-U. Schroeder, and J. A. K. Hyttinen, “Comparison between simulations of In vitro 2D MEA experiments with frontal cortex tissue of embryonic mice and of neuronal cell network derived from hPSCs cells,” Neuroscience 2013, Nov 9-13, 2013, San Diego, CA.
N. Broguiere, G. Palazzolo, M. Zenobi-Wong, “Functionalized polyethylene glycol hydrogels optimized for 3D neurite outgrowth of cortical and hippocampal neurons,” The 6th International IEEE/EMBS Conference on Neural Engineering, San Diego, CA, Nov. 5-8, 2013. Abstract.
H. Dermutz, M. J. Aebersold, J. F. Saenz Cogollo, L. Demkó, T. Zambelli, and J. Vörös, “Chemical stimulation of single neurons in an in vitro system: Coupling a force-controlled nanopipette with a MEA recording system,” The 6th International IEEE/EMBS Conference on Neural Engineering, San Diego, CA, Nov. 5-8, 2013. Abstract.
K. Lenk, B. Priwitzer, L. Ylä-Outinen, L. Tietz, S. Narkilahti, and J. A.K. Hyttinen, “Simulation of Maturating Neuronal Networks Derived from hPSCs,” The 6th International IEEE/EMBS Conference on Neural Engineering, San Diego, CA, Nov. 5-8, 2013. Abstract.
G. Palazzolo, N. Broguiere, H. Dermutz, J. Becher, M. Schnabelrauch, and M. Zenobi-Wong, “Alginate sulfate provides molecular and physical cues for the induction of a 3D neuronal network,” The 6th International IEEE/EMBS Conference on Neural Engineering, San Diego, CA, Nov. 5-8, 2013. Abstract.
J. M. A. Tanskanen, V. Raatikainen, S. Narkilahti, and J. A. K. Hyttinen, “Phase lock analysis of signals from neuronal networks on multi-well microelectrode array with a common group/reference,” The 6th International IEEE/EMBS Conference on Neural Engineering, San Diego, CA, Nov. 5-8, 2013.
T. Harczos and A. Chilian, “Cochlear implant speech processing strategy based on a model of the human peripheral auditory system,” 2013 Conference on Implantable Auditory Prostheses, Lake Tahoe, CA, July 14-19, 2013, pp. 286. Download the program with abstracts.
L. Demkó, V. Hoop, A. Popert, H. Dermutz, and J. Vörös, “Towards a fully flexible system for studying hybrid networks with controlled topology,” Biological Surfaces and Interfaces, Sant Feliu de Guixols, Spain, June 30-July 5, 2013.
M. J. Aebersold, H. Dermutz, J. F. Saenz Cogollo, L. Demkó, T. Zambelli, and J. Vörös, “Stimulating neuronal cultures by local release of neurotransmitters using the FluidFM as a forcecontrolled nanopipette combined with MEAs for electrical activity recording,” UK Scanning Probe Microscopy Meeting 2013, Leeds, UK, June 26-27, 2013.
G. Palazzolo, N. Broguiere, J. Becher, M. Schnabelrauch, M. Zenobi-Wong, “Sulfation of alginate promotes 3D neuronal growth,” in Program and Abstract, 19th Swiss Conference on Biomaterials, Davos, Switzerland, June 25-26, 2013, pp. 62.
M. Pajunen, T. Joki, L. Ylä-Outinen, M. Varjola, H. Skottman, and S. Narkilahti, “3D cultures for human pluripotent stem cell -derived neuronal cells,” 11th Annual Meeting of International Society for Stem Cell Research, Boston, MA, June 12-15, 2013. Abstract.
Demkó, V. Hoop, A. Popert, H. Dermutz, and J. Vörös, “2D patterned neuronal networks,” Gordon Research Conference on Excitatory Synapses & Brain Function, Les Diablerets, Switzerland, June 9-14, 2013.
Demkó, V. Hoop, A. Popert, H. Dermutz, and J. Vörös, “2D patterned neuronal networks,” Gordon Research Conference on Dendrites: Molecules, Structure & Function, Les Diablerets, Switzerland, May 19-24, 2013.
H. Dermutz, J. Saenz, and J. Vörös, High precision release of neurotransmitter – A new tool,” 57th Annual Meeting of the Biophysical Society, Philadelphia, PA, Feb. 2-6, 2013. Abstract in Biophysical Journal, vol. 104, no. 2, Suppl. 1, Jan 2013, pp. 498a.
Keynote Speeches, Invited Talks, and Other Oral Presentations
J. Hyttinen, “ Welcome & Introduction to 3D in vitro technologies – Case: 3DNeuroN,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
N. Broguiere, “3D neural networks in engineered hydrogel matrices,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
J. Vörös, “Forming neuron networks with controlled topology in 2D and 3D,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
S. Narkilahti, “Role of astrocytes in formation of functional neuronal networks in vitro Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
K. Lenk, “Computational modeling of neuronal-astrocytic networks,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
P. Husar, “Signal acquisition and measurement system for neural networks in vitro,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
H. Bartsch, “Technology and material developments for 3D multielectrode arrays,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
Sukhdeep Singh, “Microbioreactor designs with integrated 3D MEA devices for cultivation of neuronal cells,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
P. Husar, “Investigation of cultured neuronal networks and their dynamics induced by novel stimulation paradigms,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
J. Tanskanen, “Signal analysis methods for neuronal microelectrode array data,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
K. Lenk, “Computational modeling from 2D to 3D networks,” Bernstein Conference Satellite Symposium No. 8, “In vitro neuronal networks from 2D to 3D”, Heidelberg, Germany, Sept. 14, 2015.
S. Narkilahti, “Human stem-cell derived neuronal cell based in vitro platforms for neurotoxicity and disease modelling,” in Proc. 9th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, July 1-4, 2014, pp. 348-350. Download the Proceedings.
S. Narkilahti, “Imaging and analysis of human neuronal networks in vitro,” Live cell Imaging seminar, 21.05.2014, St. Petersburg, Russia.
S. Narkilahti, “Culturing of neural cells in 3D,” NanoForum, 16.05.2014, Helsinki.
S. Narkilahti, “Can neurons communicate in a laborartory dish?,” CIMO Winter School, 05.03.2014, Tvärminne, Finland.
S. Narkilahti, “Imaging and analysis of human neuronal networks in vitro,” Live cell Imaging course, 26.02.2014, Oswestry, Wales, UK.
K. Lenk, “Simulation of neuronal activity of human embryonic stem cells recorded with multielectrode arrays,” Invited Talk presented at 3rd International Conference „Aspects of Neuroscience”, University of Warsaw, Poland, Nov. 2013. Abstract.
S. Narkilahti, “Human pluripotent stem cells derived neural cells,” Oral Presentation in a seminar series, 8.10.2013, University of Georgia, USA.
S. Narkilahti, “Human stem cell-based micro-electrode array (MEA) platform for studying in vitro (developmental) neurotoxicity,” Invited Talk presented at Neurodevelopmental Basis of Heath and Disease INA Meeting, 12.6.2013, Holland.
J. Hyttinen, “Engineering approaches for stem cell technology – from bioelectric environments to computational modelling,” Invited Talk presented in Kolloquium über Biomedizinische Technik und verwandte Gebiete, Helmholtz-Institute for Biomedical Engineering at RWTH Aachen University, Aachen, Germany, 6.6.2013.
J. Hyttinen, “Bioelectric environments for stem cell derived neurons and cardiomyocytes,” Keynote Speech presented at Biomedical Engineering / Biomedizinische Technik, vol. 57, issue SI-1, Proc. 4The 6th DGBMT Annual Conference, German Society of Biomedical Engineering within VDE, Jena, Germany, 16.-19.9.2012, pp. 169. Abstract.
Master’s and Bachelor’s Theses
K. Albrecht, Untersuchung interzellulärer Kopplung neuronaler Zellkulturen mittels Transferentropie. Master’s Thesis. Ilmenau University of Technology, 2015. Publication record. / Abstract.
K. Kring, Analyse neuronaler in-vitro Netzwerke mittels Higher-Order Spektren. Master’s Thesis. Ilmenau University of Technology, 2015. Publication record. / Abstract.
J. Hunold, Echtzeitfähige Signalanalysen neuronaler Zellaktivitäten in LabVIEW. Bachelor’s Thesis. Ilmenau University of Technology, 2015. Publication record. / Abstract.
S. Stoor, Kausalitätsanalyse und Quellenverfolgung neuronaler Aktivitäten in vitro. Master’s Thesis. Ilmenau University of Technology, 2014. Publication record. / Abstract.
T. Kautz, Detektion und Clusteranalyse neuronaler Spikes auf Basis mehrdimensionaler Zerlegungsverfahren. Master’s Thesis. Ilmenau University of Technology, 2013. Publication record. / Abstract.